BGC > CAS Search > 868540-17-4

Molecular Formula: C40H57N5O7
Molecular Weight: 719.90988
HS Code: 29337900

Molecular Formula: C40H57N5O7
Molecular Weight: 719.90988
HS Code: 29337900

Molecular Formula: C40H57N5O7
Molecular Weight: 719.90988
HS Code: 29337900

Description :
Carfilzomib is a tetrapeptide epoxyketone and an analog of epoxomicin, acting as a selective proteasome inhibitor, such as the chymotrypsin-like β5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and the β5i subunit of the immunoproteasome 20Si (LMP7; IC50 = 14 nM). It has been used as an injectable antineoplastic agent (IV only).

• Molecular Weight :719.9
• Boiling Point :975.6±65.0 °C at 760 mmHg
• Melting Point :204-208°C
• Purity :≥98%

Molecular Formula :
C40H57N5O7
Canonical SMILES :
CC(C)CC(C(=O)C1(CO1)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
InChI :
InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1
InChIKey :
BLMPQMFVWMYDKT-NZTKNTHTSA-N
Appearance :
White to Off-white Solid
Synonyms :
Kyprolis; PR171; PR-171; PR 171; (2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide

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