BGC > Product Search > Donepezil

Molecular Formula: C24H29NO3
Molecular Weight: 379,49

EINECS :601-651-9
Molecular formula :C24H29NO3

EINECS :601-651-9
Molecular formula :C24H29NO3

EINECS :601-651-9
Molecular formula :C24H29NO3

Description :
Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase.

• Molecular Weight :379.49
• Boiling Point :527.9±50.0 °C (Predicted)
• Melting Point :207 °C
• Purity :> 98%

Molecular Formula :
C24H29NO3
Canonical SMILES :
COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC
InChI :
InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
InChIKey :
ADEBPBSSDYVVLD-UHFFFAOYSA-N
Solubility :
Slightly soluble in Acetone, Chloroform, Water (2.93 mg/L at 25 °C )
Appearance :
White to Off-white Solid
Storage : -20 °C
Synonyms :
2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE

More details are to be found here

Description :
Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase.

• Molecular Weight :379.49
• Boiling Point :527.9±50.0 °C (Predicted)
• Melting Point :207 °C
• Purity :> 98%

Molecular Formula :
C24H29NO3
Canonical SMILES :
COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC
InChI :
InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
InChIKey :
ADEBPBSSDYVVLD-UHFFFAOYSA-N
Solubility :
Slightly soluble in Acetone, Chloroform, Water (2.93 mg/L at 25 °C )
Appearance :
White to Off-white Solid
Storage : -20 °C
Synonyms :
2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE

More details are to be found here

Purity : 98%
Smile code : C1=C2C(=CC(=C1OC)OC)CC(C2=O)CC4CCN(CC3=CC=CC=C3)CC4
MDL Number : MFCD00912833
MolFormula : C24H29NO3
MolWeight : 379.4920
Available in stock : 840.276

More details are to be found here

Purity : 98%
Smile code : C1=C2C(=CC(=C1OC)OC)CC(C2=O)CC4CCN(CC3=CC=CC=C3)CC4
MDL Number : MFCD00912833
MolFormula : C24H29NO3
MolWeight : 379.4920
Available in stock : 840.276

More details are to be found here