www.BuyersGuideChem.com - the directory of chemicals and chemical suppliers. The search engine opens a large data base and offers new supply sources
Welcome About BGC Terms of Use MSDS Banner Adverts Statistics Impressum Sitemap
BGC > Product Search > Sorafenib tosylate
english deutsch español

Suppliers for

Sorafenib tosylate



Properties

CAS   475207-59-1 
Formula   C21H16ClF3N4O3.C7H8SO3 

Structure

23 Registered suppliers


Appearance Pale Yellow or almost white crystalline powder
Melting point 225.0-235.0℃
Solubility Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly in water.
Identification
(1) MS
(2) UV
(3) 1H-NMR
Loss on drying ≤ 0.5%
Heavy metals ≤ 10ppm
Ordinary impurities
Total impurities ≤ 1.0%
Assay(HPLC) 99.0%~101.0%


Appearance Pale Yellow or almost white crystalline powder
Melting point 225.0-235.0℃
Solubility Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly in water.
Identification
(1) MS
(2) UV
(3) 1H-NMR
Loss on drying ≤ 0.5%
Heavy metals ≤ 10ppm
Ordinary impurities
Total impurities ≤ 1.0%
Assay(HPLC) 99.0%~101.0%


Appearance Pale Yellow or almost white crystalline powder
Melting point 225.0-235.0℃
Solubility Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly in water.
Identification
(1) MS
(2) UV
(3) 1H-NMR
Loss on drying ≤ 0.5%
Heavy metals ≤ 10ppm
Ordinary impurities
Total impurities ≤ 1.0%
Assay(HPLC) 99.0%~101.0%


Molecular Formula: C21H16ClF3N4O3
Molecular Weight: 464.83
HS Code: 29350090

More details are to be found here
Molecular Formula: C21H16ClF3N4O3
Molecular Weight: 464.83
HS Code: 29350090

More details are to be found here


More details are to be found here


More details are to be found here
Description :
Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.
  • Molecular Weight :637.03
  • Boiling Point :523.3 °C at 760 mmHg
  • Melting Point :229-232 °C
  • Purity :≥ 95%
Molecular Formula :
C28H24ClF3N4O6S
Canonical SMILES :
CC1=CC=C(C=C1)S(=O)(=O)O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
InChI :
InChI=1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10)
InChIKey :
IVDHYUQIDRJSTI-UHFFFAOYSA-N
Solubility :
Soluble in Methanol, DMSO, DMF
Appearance :
White to Off-white Solid
Storage : 2-8 °C
Synonyms :
Sorafenib p-toluenesulfonate; BAY 43-9006 Mono-p-tosylate; BAY 54-9085; Nexavar(R); 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate); 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate); Bay 43-9006

More details are to be found here


More details are to be found here


More details are to be found here


More details are to be found here


More details are to be found here

Detailed information on the suppliers of Sorafenib tosylate

Properties:

... more properties and specification on Sorafenib tosylate
© Copyright 1996 to 2024 by Netvertise GmbH. All rights reserved