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Suppliers for
Sorafenib tosylate
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Properties | CAS |
475207-59-1 | Formula |
C21H16ClF3N4O3.C7H8SO3 |
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23 Registered suppliers
Appearance | Pale Yellow or almost white crystalline powder
| Melting point | 225.0-235.0℃
| Solubility | Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly in water.
| Identification |
| (1) MS |
| (2) UV |
| (3) 1H-NMR |
| Loss on drying | ≤ 0.5%
| Heavy metals | ≤ 10ppm
| Ordinary impurities |
| Total impurities | ≤ 1.0%
| Assay(HPLC) | 99.0%~101.0% |
Appearance | Pale Yellow or almost white crystalline powder
| Melting point | 225.0-235.0℃
| Solubility | Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly in water.
| Identification |
| (1) MS |
| (2) UV |
| (3) 1H-NMR |
| Loss on drying | ≤ 0.5%
| Heavy metals | ≤ 10ppm
| Ordinary impurities |
| Total impurities | ≤ 1.0%
| Assay(HPLC) | 99.0%~101.0% |
Appearance | Pale Yellow or almost white crystalline powder
| Melting point | 225.0-235.0℃
| Solubility | Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly in water.
| Identification |
| (1) MS |
| (2) UV |
| (3) 1H-NMR |
| Loss on drying | ≤ 0.5%
| Heavy metals | ≤ 10ppm
| Ordinary impurities |
| Total impurities | ≤ 1.0%
| Assay(HPLC) | 99.0%~101.0% |
Appearance | Pale Yellow or almost white crystalline powder
| Melting point | 225.0-235.0℃
| Solubility | Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol; very poorly in water.
| Identification |
| (1) MS |
| (2) UV |
| (3) 1H-NMR |
| Loss on drying | ≤ 0.5%
| Heavy metals | ≤ 10ppm
| Ordinary impurities |
| Total impurities | ≤ 1.0%
| Assay(HPLC) | 99.0%~101.0% |
More details are to be found here
Molecular Formula: C21H16ClF3N4O3 Molecular Weight: 464.83 HS Code: 29350090
More details are to be found here
Molecular Formula: C21H16ClF3N4O3 Molecular Weight: 464.83 HS Code: 29350090
More details are to be found here
Molecular Formula: C21H16ClF3N4O3 Molecular Weight: 464.83 HS Code: 29350090
More details are to be found here
More details are to be found here
More details are to be found here
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Description : Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. - Molecular Weight :637.03
- Boiling Point :523.3 °C at 760 mmHg
- Melting Point :229-232 °C
- Purity :≥ 95%
Molecular Formula : C28H24ClF3N4O6S Canonical SMILES : CC1=CC=C(C=C1)S(=O)(=O)O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F InChI : InChI=1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10) InChIKey : IVDHYUQIDRJSTI-UHFFFAOYSA-N Solubility : Soluble in Methanol, DMSO, DMF Appearance : White to Off-white Solid Storage : 2-8 °C Synonyms : Sorafenib p-toluenesulfonate; BAY 43-9006 Mono-p-tosylate; BAY 54-9085; Nexavar(R); 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate); 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate); Bay 43-9006
More details are to be found here
Description : Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. - Molecular Weight :637.03
- Boiling Point :523.3 °C at 760 mmHg
- Melting Point :229-232 °C
- Purity :≥ 95%
Molecular Formula : C28H24ClF3N4O6S Canonical SMILES : CC1=CC=C(C=C1)S(=O)(=O)O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F InChI : InChI=1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10) InChIKey : IVDHYUQIDRJSTI-UHFFFAOYSA-N Solubility : Soluble in Methanol, DMSO, DMF Appearance : White to Off-white Solid Storage : 2-8 °C Synonyms : Sorafenib p-toluenesulfonate; BAY 43-9006 Mono-p-tosylate; BAY 54-9085; Nexavar(R); 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate); 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate); Bay 43-9006
More details are to be found here
Purity : 98% Smile code : O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=C1)NC.O=S(C4=CC=C(C)C=C4)(O)=O MDL Number : MFCD08235032 MolFormula : C28H24ClF3N4O6S MolWeight : 637.0266 Available in stock : 426.768
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Last update 2024-05-31
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