BGC > Product Search > Azelastine hydrochloride

Molecular Formula: C22H24ClN3O.HCl
Molecular Weight: 418,36

Description :
Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.

• Molecular Weight :418.36
• Melting Point :223-225°C
• Purity :> 98%

Molecular Formula :
C22H25Cl2N3O
Canonical SMILES :
[H+].CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.[Cl-]
InChI :
InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
InChIKey :
YEJAJYAHJQIWNU-UHFFFAOYSA-N
Solubility :
In Vitro: DMSO : 50 mg/mL(119.51 mM;Need ultrasonic) H2O : 6.67 mg/mL(15.94 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution
Appearance :
White Solid
Application :
histamine antagonist
Storage : 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture)
Synonyms :
ZELASTINE HYDROCHLORIDE; AC1Q1SYE; HYDROGEN AZELASTINE CHLORIDE; AKOS026749829; DR002552

More details are to be found here

Description :
Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.

• Molecular Weight :418.36
• Melting Point :223-225°C
• Purity :> 98%

Molecular Formula :
C22H25Cl2N3O
Canonical SMILES :
[H+].CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.[Cl-]
InChI :
InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
InChIKey :
YEJAJYAHJQIWNU-UHFFFAOYSA-N
Solubility :
In Vitro: DMSO : 50 mg/mL(119.51 mM;Need ultrasonic) H2O : 6.67 mg/mL(15.94 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution
Appearance :
White Solid
Application :
histamine antagonist
Storage : 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture)
Synonyms :
ZELASTINE HYDROCHLORIDE; AC1Q1SYE; HYDROGEN AZELASTINE CHLORIDE; AKOS026749829; DR002552

More details are to be found here

Description :
Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.

• Molecular Weight :418.36
• Melting Point :223-225°C
• Purity :> 98%

Molecular Formula :
C22H25Cl2N3O
Canonical SMILES :
[H+].CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.[Cl-]
InChI :
InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
InChIKey :
YEJAJYAHJQIWNU-UHFFFAOYSA-N
Solubility :
In Vitro: DMSO : 50 mg/mL(119.51 mM;Need ultrasonic) H2O : 6.67 mg/mL(15.94 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution
Appearance :
White Solid
Application :
histamine antagonist
Storage : 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture)
Synonyms :
ZELASTINE HYDROCHLORIDE; AC1Q1SYE; HYDROGEN AZELASTINE CHLORIDE; AKOS026749829; DR002552

More details are to be found here

Purity : 98%
Smile code : O=C1N(C2CCN(C)CCC2)N=C(CC3=CC=C(Cl)C=C3)C4=C1C=CC=C4.[H]Cl
MDL Number : MFCD00242783
MolFormula : C22H25Cl2N3O
MolWeight : 418.3594
Available in stock : 988.636

More details are to be found here

Purity : 98%
Smile code : O=C1N(C2CCN(C)CCC2)N=C(CC3=CC=C(Cl)C=C3)C4=C1C=CC=C4.[H]Cl
MDL Number : MFCD00242783
MolFormula : C22H25Cl2N3O
MolWeight : 418.3594
Available in stock : 988.636

More details are to be found here

Purity : 98%
Smile code : O=C1N(C2CCN(C)CCC2)N=C(CC3=CC=C(Cl)C=C3)C4=C1C=CC=C4.[H]Cl
MDL Number : MFCD00242783
MolFormula : C22H25Cl2N3O
MolWeight : 418.3594
Available in stock : 988.636

More details are to be found here